Which lab value is listed as a high value in nephrotic syndrome labs?

Which lab value is listed as a high value in nephrotic syndrome labs?

• A. Low platelet count
• B. Hb WNL
• C. High platelet count
• D. Low sodium

Answer: (C)

Nephrotic syndrome often sets up a prothrombotic state. Loss of anticoagulant proteins in the urine, like antithrombin III, combined with the liver’s increased production of coagulation factors and fibrinogen, makes blood more prone to clotting. In this hypercoagulable milieu, platelets can rise as a reactive change, so a high platelet count is a lab finding you might see. The other options don’t typically present as elevated in this context: platelets would not be high if thrombocytopenia were occurring; hemoglobin is usually normal or low rather than high; and sodium is not characteristically elevated in nephrotic labs.

Nephrotic syndrome often sets up a prothrombotic state. Loss of anticoagulant proteins in the urine, like antithrombin III, combined with the liver’s increased production of coagulation factors and fibrinogen, makes blood more prone to clotting. In this hypercoagulable milieu, platelets can rise as a reactive change, so a high platelet count is a lab finding you might see. The other options don’t typically present as elevated in this context: platelets would not be high if thrombocytopenia were occurring; hemoglobin is usually normal or low rather than high; and sodium is not characteristically elevated in nephrotic labs.